3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid

Name	Mal-PEG2-acid
Synonyms	Mal-PEG2-acid Mal-NH-PEG2-acid Mal-PEG2-CH2CH2COOH Maleimide-PEG2-CH2CH2COOH α-Maleimidyl-ω-propionyloxy poly(ethylene glycol) 3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid 3-[2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic acid Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-
CAS	1374666-32-6

Molecular Formula	C11H15NO6
Molar Mass	257.24
Density	1.329±0.06 g/cm3(Predicted)
Boling Point	455.7±35.0 °C(Predicted)
pKa	4.27±0.10(Predicted)
Storage Condition	Room Temprature
Physical and Chemical Properties	Bioactive Mal-PEG2-acid is a non-cleavable ADC linker used to synthesize antibody-coupled drugs (ADC). Mal-PEG2-acid can be active with Tubulysin (HY-128914) and its cytotoxic derivatives. Mal-PEG2-acid can also be used as PROTAC linker for PROTAC synthesis.
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

biological activity	Mal-PEG2-acid is a non-cleavable ADC linker used to synthesize antibody-coupled drugs (ADC). Mal-PEG2-acid can be active with Tubulysin (HY-128914) and its cytotoxic derivatives. Mal-PEG2-acid can also be used as PROTAC linker for PROTAC synthesis.
target	Non-cleavable PEGs
in vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-09 19:55:45

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CAS: 1374666-32-6
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409

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3-[2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoic Acid Request for Quotation